Design of combinatorial protein libraries of optimal size
نویسندگان
چکیده
منابع مشابه
Design of combinatorial protein libraries of optimal size.
In this article we introduce a computational procedure, OPTCOMB (Optimal Pattern of Tiling for COMBinatorial library design), for designing protein hybrid libraries that optimally balance library size with quality. The proposed procedure is directly applicable to oligonucleotide ligation-based protocols such as GeneReassembly, DHR, SISDC, and many more. Given a set of parental sequences and the...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2005
ISSN: 0887-3585
DOI: 10.1002/prot.20490